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Neurotrophic Natural Products (Progress in the Chemistry of Organic Natural Products, 123)
Tác giả: A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch
NXB: Springer
Chi tiết sản phẩm
Mô tả nội dung sách Neurotrophic Natural Products (Progress in the Chemistry of Organic Natural Products, 123) - A. Douglas Kinghorn
Thông tin sách: Neurotrophic Natural Products (Progress in the Chemistry of Organic Natural Products, 123) (Kindle, 482 trang) – Springer, 2024. Ngôn ngữ: Tiếng Anh.
This book deals with neurotrophins (NGF, BDNF, NT3, NT4), which can decrease cell death, induce differentiation, as well as sustain the structure and function of neurons. This makes neurotrophins potential therapeutic agents for the treatment of neurodegenerative disorders. However, these proteins have so far been ineffective in clinical trials mostly because they cannot pass the blood-brain barrier owing to their high-molecular weights. Consequently, small molecules that mimic neurotrophins and stimulate the synthesis of endogenous neurotrophins or enhance their neurotrophic actions are expected to be promising alternatives. Small-molecule natural products, which have been used in dietary functional foods or in traditional medicine over the course of human history, have potential to be developed as new therapeutic agents against neurodegenerative conditions such as Alzheimer’s disease. In this book, the authors introduce a variety of natural products possessing neurotrophic properties such as neurogenesis, neurite outgrowth promotion (neuritogenesis), and neuroprotection and focus on the chemistry and biology of several neurotrophic natural products.
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6.452.000 ₫
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Sách cùng tác giả A. Douglas Kinghorn
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