Human Blood Plasma Proteins: Structure and Function

Thông tin sách: Human Blood Plasma Proteins: Structure and Function (Hardcover, 544 trang) – Wiley, 2008. Ngôn ngữ: Tiếng Anh.

Human Blood Plasma Proteins gives an overview of the proteins found in human blood plasma, with special emphasis on their structure and function and relationship to pathological states and disease. Topics covered include:

• introduction to blood components and blood plasma proteins
• blood plasma protein domains, motifs and repeats
• blood plasma protein families and posttranslational modifications
• blood coagulation and fibrinolysis
• the complement system
• the immune system
• enzymes
• inhibitors
• lipoproteins
• hormones
• cytokines and growth factors
• transport and storage

The information of each protein discussed in this book in some detail is summarised at the end of each chapter in a Data Sheet, where one can find the most important data of each protein at one glance. Full cross-referencing to protein databases is given and many of the proteins discussed are accompanied by their 3D structure.

Attractively presented in full colour, Human Blood Plasma Proteins is an essential atlas of this proteome for anyone working in biochemistry, protein chemistry and proteomics, structural biology, and medicine.

From the Back Cover Human plasma contains the most comprehensive version of the human proteome. The complexity of the ‘plasma proteome’ is quickly understood when one considers all the various forms of blood plasma proteins present in plasma: precursor and mature forms, splice variants, degradation products and of course all combinations of posttranslational modifications.

Human Blood Plasma Proteins gives an overview of the proteins found in human blood plasma, with special emphasis on their structure and function and relationship to pathological states and disease. Topics covered include:

• Introduction to blood components and blood plasma proteins
• Blood plasma protein domains, motifs and repeats
• Blood plasma protein families and posttranslational modifications
• Blood coagulation and fibrinolysis
• The complement system
• The immune system
• Enzymes
• Inhibitors
• Lipoproteins
• Hormones
• Cytokines and growth factors
• Transport and storage

The information of each protein discussed in this book in some detail is summarised at the end of each chapter in a Data Sheet, where one can find the most important data of each protein at one glance. Full cross-referencing to protein databases is given and many of the proteins discussed are accompanied by their 3D structure.

Human Blood Plasma Proteins is an essential atlas of this proteome for anyone working in biochemistry, protein chemistry and proteomics, structural biology, and medicine.

About the Author

Johann Schaller, Department of Chemistry & Biochemistry, University of Bern, Switzerland.

Simon Gerber, Department of Chemistry & Biochemistry, University of Bern, Switzerland.

Urs Kaempfer, Department of Chemistry & Biochemistry, University of Bern, Switzerland.

Sofia Lejon, Department of Chemistry & Biochemistry, University of Bern, Switzerland.

Christian Trachsel, Department of Chemistry & Biochemistry, University of Bern, Switzerland.